ПАТОГЕНЕТИЧНІ ОСОБЛИВОСТІ КОНТРОЛЮ ЗА ПЕРЕБІГОМ ПРЕЕКЛАМПСІЇ У ВАГІТНИХ ТА ЇЇ ВПЛИВ НА СЕРЦЕВО-СУДИННУ СИСТЕМУ (ОГЛЯД ЛІТЕРАТУРИ)
DOI:
https://doi.org/10.24061/1727-4338.XXI.2.80.2022.9Ключові слова:
вагітність, прееклампсія, серцева недостатність, материнська смертність, кардіоміопатіяАнотація
Мета роботи – проаналізувати сучасні погляди на патогенетичні особливості
контролю за перебігом прееклампсії у вагітних, роль NT-proBNP у її патогенезі
та можливості профілактики.
Висновок. Показана необхідність подальшого вивчення цієї проблеми з метою
пролонгування вагітності до терміну доношеності у жінок із прееклампсією.
Посилання
Ananth CV, Keyes KM, Wapner RJ. Pre-eclampsia rates in the
United States, 1980-2010: age-period- cohort analysis. BMJ
[Internet]. 2013[cited 2022 May 31];347: f6564. Available from:
https://www.bmj.com/content/347/bmj.f6564.long doi: 10.1136/
bmj.f6564
Fox A, McHugh S, Browne J, Kenny LC, Fitzgerald A, Khashan AS,
et al. Estimating the cost of preeclampsia in the healthcare system:
cross- sectional study using data from SCOPE study (Screening
for Pregnancy End Points). Hypertension. 2017;70(6):1243-9.
doi: 10.1161/hypertensionaha.117.09499
Davis EF, Lazdam M, Lewandowski AJ, Worton SA, Kelly B,
Kenworthy Y, et al. Cardiovascular risk factors in children and
young adults born to preeclamptic pregnancies: a systematic review.
Pediatrics. 2012;129(6): e1552-61. doi: 10.1542/peds.2011-3093
Maher GM, O’Keeffe GW, Kearney PM, Kenny LC, Dinan
TG, Mattsson M, et al. Association of hypertensive disorders of
pregnancy with risk of neurodevelopmental disorders in offspring:
a systematic review and meta-analysis. JAMA Psychiatry.
;75(8):809-19. doi: 10.1001/jamapsychiatry.2018.0854
Behrens I, Basit S, Melbye M, Lykke JA, Wohlfahrt J, Bundgaard H,
et al. Risk of post-pregnancy hypertension in women with a history of
hypertensive disorders of pregnancy: nationwide cohort study. BMJ
[Internet]. 2017[cited 2022 May 30];358: j3078. Available from:
https://www.bmj.com/content/358/bmj.j3078 doi: 10.1136/bmj.j3078
Scantlebury DC, Kattah AG, Weissgerber TL, Agarwal S, Mielke
MM, Weaver AL, et al. Impact of a history of hypertension in
pregnancy on later diagnosis of atrial fibrillation. J Am Heart Assoc
[Internet]. 2018[cited 2022 Jun 03];7(10): e007584. Available
from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015308/
pdf/JAH3-7-e007584.pdf doi: 10.1161/jaha.117.007584
Theilen LH, Meeks H, Fraser A, Esplin MS, Smith KR, Varner
MW. Long-term mortality risk and life expectancy following
recurrent hypertensive disease of pregnancy. Am J Obstet Gynecol
[Internet]. 2018[cited 2022 Jun 05];219(1):107. Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019643/pdf/
nihms963558.pdf doi: 10.1016/j.ajog.2018.04.002
Tooher J, Thornton C, Makris A, Ogle R, Korda A, Hennessy
A. All hypertensive disorders of pregnancy increase the risk of
future cardiovascular disease. Hypertension. 2017;70(4):798-803.
doi: 10.1161/hypertensionaha.117.09246
Romundstad PR, Magnussen EB, Smith GD, Vatten LJ.
Hypertension in pregnancy and later cardiovascular risk: common
antecedents? Circulation. 2010;122(6):579-84. doi: 10.1161/
circulationaha.110.943407
Giannakou K, Evangelou E, Papatheodorou SI. Genetic and
non-genetic risk factors for pre-eclampsia: umbrella review of
systematic reviews and meta-analyses of observational studies.
Ultrasound Obstet Gynecol. 2018;51(6):720-30. doi: 10.1002/
uog.18959
Serrano NC, Guio- Mahecha E, Quintero- Lesmes DC, BecerraBayona S, Paez MC, Beltran M, et al. Lipid profile, plasma
apolipoproteins, and pre-eclampsia risk in the GenPE casecontrol study. Atherosclerosis. 2018;276:189-94. doi: 10.1016/j.
atherosclerosis.2018.05.051
Egeland GM, Klungsøyr K, Øyen N, Tell GS, Næss Ø, Skjærven
R. Preconception cardiovascular risk factor differences between
gestational hypertension and preeclampsia: cohort norway
study. Hypertension. 2016;67(6):1173-80. doi: 10.1161/
hypertensionaha.116.07099
Thilaganathan B. Pre-eclampsia and the cardiovascular- placental
axis. Ultrasound Obstet Gynecol. 2018;51(6):714-7. doi: 10.1002/
uog.19081
Perry H, Khalil A, Thilaganathan B. Preeclampsia and the
cardiovascular system: an update. Trends Cardiovasc Med.
;28(8):505-13. doi: 10.1016/j.tcm.2018.04.009
Kalafat E, Thilaganathan B. Cardiovascular origins of
preeclampsia. Curr Opin Obstet Gynecol. 2017;29(6):383-9. doi:
1097/gco.0000000000000419
Melchiorre K, Sharma R, Thilaganathan B. Cardiovascular
implications in preeclampsia: an overview. Circulation.
;130(8):703-14. doi: 10.1161/circulationaha.113.003664
McGinnis R, Steinthorsdottir V, Williams NO, Thorleifsson G,
Shooter S, Hjartardottir S, et al. Variants in the fetal genome
near FLT1 are associated with risk of preeclampsia. Nat Genet.
;49(8):1255-60. doi: 10.1038/ng.3895
Lokki AI, Daly E, Triebwasser M, et al. Protective low-frequency
variants for preeclampsia in the Fms related tyrosine kinase 1 gene
in the Finnish population. Hypertension. 2017;70(2):365-71. doi:
1161/hypertensionaha.117.09406
Wei J, Liu CX, Gong TT, Wu QJ, Wu L. Cigarette smoking during
pregnancy and preeclampsia risk: a systematic review and metaanalysis of prospective studies. Oncotarget. 2015;6(41):43667-78.
doi: 10.18632/oncotarget.6190
Leffler CW, Parfenova H, Jaggar JH. Carbon monoxide as an
endogenous vascular modulator. Am J Physiol Heart Circ Physiol.
;301(1): H1-11. doi: 10.1152/ajpheart.00230.2011
Heida KY, Bots ML, de Groot CJ, van Dunné FM, Hammoud
NM, Hoek A, et al. Cardiovascular risk management after
reproductive and pregnancy-related disorders: a Dutch
multidisciplinary evidence- based guideline. Eur J Prev Cardiol.
;23(17):1863-79. doi: 10.1177/2047487316659573
Hutcheon JA, Stephansson O, Cnattingius S, Bodnar LM,
Wikström AK, Johansson K. Pregnancy weight gain before
diagnosis and risk of preeclampsia: a population- based cohort
study in nulliparous women. Hypertension. 2018;72(2):433-41.
doi: 10.1161/hypertensionaha.118.10999
Kalafat E, Sukur YE, Abdi A, Thilaganathan B, Khalil A. Metformin
for the prevention of hypertensive disorders of pregnancy in women
with gestational diabetes and obesity: a systematic review and
meta-analysis. Ultrasound Obstet Gynecol. 2018;52(6):706-14.
doi: 10.1002/uog.19084
Tangren JS, Powe CE, Ankers E, Ecker J, Bramham K,
Hladunewich MA, et al. Pregnancy outcomes after clinical
recovery from AKI. J Am Soc Nephrol. 2017;28(5):1566-74. doi:
1681/asn.2016070806
Stergiotou I, Bijnens B, Cruz- Lemini M, Figueras F, Gratacos E,
Crispi F. Maternal subclinical vascular changes in fetal growth
restriction with and without pre-eclampsia. Ultrasound Obstet
Gynecol. 2015;46(6):706-12. doi: 10.1002/uog.14815
Sep SJ, Schreurs MP, Bekkers SC, Kruse AJ, Smits LJ, Peeters LL.
Early-pregnancy changes in cardiac diastolic function in women
with recurrent pre-eclampsia and in previously pre-eclamptic
women without recurrent disease. BJOG. 2011;118(9):1112-9. doi:
1111/j.1471-0528.2011.02951.x
Ghossein- Doha C, Spaanderman MEA, Al Doulah R, Van Kuijk SM,
Peeters LLH. Maternal cardiac adaptation to subsequent pregnancy
in formerly pre-eclamptic women according to recurrence of preeclampsia. Ultrasound Obstet Gynecol. 2016;47(1):96-103. doi:
1002/uog.15752
Milic NM, Milin- Lazovic J, Weissgerber TL, Trajkovic G,
White WM, Garovic VD. Preclinical atherosclerosis at the time
of pre-eclamptic pregnancy and up to 10 years postpartum:
systematic review and meta-analysis. Ultrasound Obstet Gynecol.
;49(1):110-5. doi: 10.1002/uog.17367
Song C, Burgess S, Eicher JD, O’Donnell CJ, Johnson AD. Causal
effect of plasminogen activator inhibitor type 1 on coronary
heart disease. J Am Heart Assoc [Internet]. 2017[cited 2022 May
;6(6): e004918. Available from: https://www.ncbi.nlm.nih.
gov/pmc/articles/PMC5669150/pdf/JAH3-6-e004918.pdf doi:
1161/jaha.116.004918
Odutayo A, Wong CX, Farkouh M, Altman DG, Hopewell S,
Emdin CA, et al. AKI and long-term risk for cardiovascular events
and mortality. J Am Soc Nephrol. 2017;28(1):377-87. doi: 10.1681/
asn.2016010105
Sedaghat S, van Sloten TT, Laurent S, London GM, Pannier B,
Kavousi M, et al. Common carotid artery diameter and risk of
cardiovascular events and mortality: pooled analyses of Four
cohort studies. Hypertension. 2018;72(1):85-92. doi: 10.1161/
hypertensionaha.118.11253
Goulopoulou S. Maternal vascular physiology in preeclampsia.
Hypertension. 2017;70(6):1066-73. doi: 10.1161/
hypertensionaha.117.08821
Stanhewicz AE, Jandu S, Santhanam L, Alexander LM.
Increased angiotensin II sensitivity contributes to microvascular
dysfunction in women who have had preeclampsia. Hypertension.
;70(2):382-9. doi: 10.1161/hypertensionaha.117.09386
Cunningham MW, Williams JM, Amaral L, Usry N, Wallukat G,
Dechend R, et al. Agonistic autoantibodies to the angiotensin II type
receptor enhance angiotensin II-induced renal vascular sensitivity
and reduce renal function during pregnancy. Hypertension.
;68(5):1308-13. doi: 10.1161/hypertensionaha.116.07971
Morgan HL, Butler E, Ritchie S, Herse F, Dechend R, Beattie
E, et al. Modeling superimposed preeclampsia using Ang II
(Angiotensin II) infusion in pregnant stroke- prone spontaneously
hypertensive rats. Hypertension. 2018;72(1):208-18. doi: 10.1161/
hypertensionaha.118.10935
Verdonk K, Saleh L, Lankhorst S, Smilde JE, van Ingen
MM, Garrelds IM, et al. Association studies suggest a key
role for endothelin-1 in the pathogenesis of preeclampsia
and the accompanying renin- angiotensin-aldosterone system
suppression. Hypertension. 2015;65(6):1316-23. doi: 10.1161/
hypertensionaha.115.05267
Li F, Kakoki M, Smid M, Boggess K, Wilder J, Hiller S, et al.
Causative effects of genetically determined high maternal/fetal
endothelin-1 on preeclampsia-like conditions in mice. Hypertension.
;71(5):894-903. doi: 10.1161/hypertensionaha.117.10849
Kaartokallio T, Klemetti MM, Timonen A, Uotila J, Heinonen
S, Kajantie E, et al. Microsatellite polymorphism in the heme
oxygenase-1 promoter is associated with nonsevere and lateonset preeclampsia. Hypertension. 2014;64:172-7. doi: 10.1161/
hypertensionaha.114.03337
Mousa AA, Strauss JF 3rd, Walsh SW. Reduced methylation of the
thromboxane synthase gene is correlated with its increased vascular
expression in preeclampsia. Hypertension. 2012;59(6):1249-55.
doi: 10.1161/hypertensionaha.111.188730
Rolnik DL, Wright D, Poon LCY, Syngelaki A, O’Gorman
N, de Paco Matallana C, et al. ASPRE trial: performance of
screening for preterm pre-eclampsia. Ultrasound Obstet Gynecol.
;50(4):492-5. doi: 10.1002/uog.18816
Kalafat E, Laoreti A, Khalil A, Da Silva Costa F, Thilaganathan
B. Ophthalmic artery Doppler for prediction of pre-eclampsia:
systematic review and meta-analysis. Ultrasound Obstet Gynecol.
;51(6):731-7. doi: 10.1002/uog.19002
Weissgerber TL, Milic NM, Milin- Lazovic JS, Garovic VD.
Impaired flow-mediated dilation before, during, and after
preeclampsia: a systematic review and meta-analysis. Hypertension.
;67(2):415-23. doi: 10.1161/hypertensionaha.115.06554
Porto LB, Brandão AHF, Leite HV, Cabral ACV. Longitudinal
evaluation of uterine perfusion, endothelial function and central
blood flow in early onset pre-eclampsia. Pregnancy Hypertens.
;10:161-4. doi: 10.1016/j.preghy.2017.08.005
Turanov AA, Lo A, Hassler MR, Makris A, Ashar- Patel A,
Alterman JF, et al. RNAi modulation of placental sFLT1 for the
treatment of preeclampsia. Nat Biotechnol [Internet]. 2018[cited
May 31];10.1038/nbt.4297. Available from: https://www.
ncbi.nlm.nih.gov/pmc/articles/PMC6526074/pdf/nihms-1509064.
pdf doi: 10.1038/nbt.4297
Ministerstvo okhorony zdorov’ia Ukrainy. Pro Zatverdzhennia
Unifikovanoho klinichnoho protokolu pervynnoi, vtorynnoi
(spetsializovanoi) ta tretynnoi (vysokospetsializovanoi)
medychnoi dopomohy «Hipertenzyvni rozlady pid chas
vahitnosti, polohiv ta u pisliapolohovomu periodi». Nakaz
Ministerstva okhorony zdorov’ia Ukrainy vid 24.01.2022 № 151
[On Approval of the Unified Clinical Protocol of Primary,
Secondary (Specialized) and Tertiary (Highly Specialized)
Medical Care «Hypertensive Disorders during Pregnancy,
Childbirth and the Postpartum Period». Order of the Ministry
of Health of Ukraine dated 24.01.2022 № 151] [Internet]. Kyiv:
MOZ Ukrainy; 2022[tsytovano 2022 Tra 30]. Dostupno: https://
moz.gov.ua/uploads/7/35591-dn_151_24_01_2022_dod.pdf
(in Ukrainian)
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