РОЛЬ СИГНАЛЬНИХ ШЛЯХІВ ІНСУЛІНУ В ЗАБЕЗПЕЧЕННІ ФІЗІОЛОГІЧНОГО СТАНУ ГОЛОВНОГО МОЗКУ ТА НЕЙРОПРОТЕКЦІЇ ПРИ ГОСТРИХ ПОРУШЕННЯХ МОЗКОВОГО КРОВООБІГУ
DOI:
https://doi.org/10.24061/1727-4338.XXI.2.80.2022.10Ключові слова:
мозок, сигнальні шляхи інсуліну, ішемія-реперфузія головного мозкуАнотація
Мета роботи – здійснити аналіз даних світової літератури стосовно ролі
сигнальних шляхів інсуліну у функціонуванні головного мозку за умов норми
та гострого порушення церебрального кровобігу.
Висновки. Згідно даних літератури множинні ефекти інсуліну в головному мозку
забезпечуються наявністю плейотропних сигнальних шляхів цього гормону.
Інсулін необхідний для підтримання нормального морфофункціонального стану
нервової тканини. За умов гострого порушення церебрального кровообігу усі відомі
насьогодніцеребральніефектиінсулінуспрямованіназабезпеченнянейропротекції,
яка реалізується полідромними механізмами.
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