DOI: https://doi.org/10.24061/1727-4338.XIII.3.49.2014.45

РАННІЙ ОНТОГЕНЕЗ - КРИТИЧНИЙ ПЕРІОД ДЛЯ «ПРОГРАМУВАННЯ» ЕНДОКРИННИХ І ГОРМОН-ЗАЛЕЖНИХ ПАТОЛОГІЙ ДОРОСЛОГО ЖИТТЯ

L. Yu. Sergienko

Анотація


Резюме. Сьогодні доведено, що шляхом епігенетичного впливу чинники навколишнього середовища здатні змінювати генетично детермінований фенотип функціональних систем людини, створюючи патогенетичне підґрунтя для розвитку численних патологій. Найбільш виразними є наслідки модифікації фенотипу при дії чинників в так звані «критичні періоди» онтогенезу. Теорія Дж.Баркера, що обґрунтовує пренатальне походження хвороб дорослого віку, отримує все більше підтверджень. Особливу зацікавленість дослідників викликають питання про наслідки впливу на плід соціально-емоційного стресу матерів на самих ранніх етапах вагітності. Даний огляд присвячено аналізу літератури з цієї проблеми.


Ключові слова


стрес вагітних; нащадки; ендокринні та гормональнозалежні патології

Повний текст:

PDF (Русский)

Посилання


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