РАННІЙ ОНТОГЕНЕЗ - КРИТИЧНИЙ ПЕРІОД ДЛЯ «ПРОГРАМУВАННЯ» ЕНДОКРИННИХ І ГОРМОН-ЗАЛЕЖНИХ ПАТОЛОГІЙ ДОРОСЛОГО ЖИТТЯ
DOI:
https://doi.org/10.24061/1727-4338.XIII.3.49.2014.45Ключові слова:
стрес вагітних, нащадки, ендокринні та гормональнозалежні патологіїАнотація
Резюме. Сьогодні доведено, що шляхом епігенетичного впливу чинники навколишнього середовища здатні змінювати генетично детермінований фенотип функціональних систем людини, створюючи патогенетичне підґрунтя для розвитку численних патологій. Найбільш виразними є наслідки модифікації фенотипу при дії чинників в так звані «критичні періоди» онтогенезу. Теорія Дж.Баркера, що обґрунтовує пренатальне походження хвороб дорослого віку, отримує все більше підтверджень. Особливу зацікавленість дослідників викликають питання про наслідки впливу на плід соціально-емоційного стресу матерів на самих ранніх етапах вагітності. Даний огляд присвячено аналізу літератури з цієї проблеми.
Посилання
Frol'kis VV. Stress-vozrast-sindrom [Stress-age syndrome]. Fiziologicheskiy zhurnal. 1991;3:3-10. (in Russian).
Frol'kis VV, Muradyan KhK. Starenie, evolyutsiya i prodlenie zhizni [Aging, evolution and life extension]. Kiev: Naukova dumka; 1992. 336 p. (in Russian).
Volkova OV, Pekarskiy MI. Embriogenez i vozrastnaya gistologiya vnutrennikh organov cheloveka [Embryogenesis and age histology of human internal organs]. Moskva: Meditsina; 1976. 415 p. (in Russian).
Furduy FI. Fiziologicheskie mekhanizmy stressa i adaptatsii pri ostrom deystvii stress-faktorov [Physiological mechanisms of stress and adaptation in the acute action of stress factors]. Kishinev: Shtiintsa; 1986. 240 p. (in Russian).
Sel'e G. Ocherki ob adaptatsionnom syndrome [Essays on Adaptation Syndrome]. Moskva: Medgiz; 1960. 254 p. (in Russian).
Sel'e G. Kontseptsiya stressa kak my ee predstavlyaem v 1976 godu. V: G. Sel'e. Novoe o gormonakh i mekhanizmakh ikh deystviya [The concept of stress as we present it in 1976]. Kiev: Naukova dumka; 1977, p. 27-51. (in Russian).
World Health Statistics 2005. Geneva: World Health Organization World; 2005. 117 p.
Svetlov TG. Teoriya kriticheskikh periodov razvitiya i ee znachenie dlya ponimaniya printsipov deystviya sredy na ontogenez [The theory of critical periods of development and its importance for understanding the principles of the environment on ontogenesis]. V: Svetlov TG. Voprosy tsitologii i obshchey fiziologii. Moskva; Leningrad; 1960, p. 263-74. (in Russian).
Barker DJ. In utero programming of chronic disease. https://www.ncbi.nlm.nih.gov/pubmed/9680492">Clin Sci (Lond). 1998 Aug;95(2):115-28.
Barker DJ, Eriksson JG, Forsén T, Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol. 2002 Dec;31(6):1235-9.
Levine S. Infantile experience and resistance to physiological stress. https://www.ncbi.nlm.nih.gov/pubmed/13467220">Science. 1957 Aug 30;126(3270):405.
Ward OB Jr, Orth JM, Weisz J. A possible role of opiates in modifying sexual differentiation. Monogr Neural Sci. 1983;9:194-200.
Ward IL. Sexual behavior: The product of perinatal hormonal and prepubertal social factors. In: Gerall AA, Moltz H, Ward IL, editors . Handbook of behavioral neurobiology. Vol. 11. Sexual differentiation. New York: Plenum Press; 1992, р. 157-80.
Dörner G, Geier T, Ahrens L, Krell L, Münx G, Sieler H, et al. Prenatal stress as possible aetiogenetic factor of homosexuality in human males. Endokrinologie. 1980 Jun;75(3):365-8.
Barker DJ, Winter PD, Osmond C, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heat disease. Lancet. 1989 Sep 9;2(8663):577-80.
Leon DA, Lithell HO, Vâgerö D, Koupilová I, Mohsen R, Berglund L, et al. Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15 000 Swedish men and women born 1915-29. BMJ. 1998 Jul 25;317(7153):241-5.
Stein CE, Fall CH, Kumaran K, Osmond C, Cox V, Barker DJ. Fetal growth and coronary heart disease in South India. Lancet. 1996 Nov 9;348(9037):1269-73.
Barker DJ, Godfrey KM, Osmond C, Bull A. The relation of fetal length, ponderal index and head circumference to blood pressure and the risk of hypertension in adult life. Paediatr Perinat Epidemiol. 1992 Jan;6(1):35-44.
Leon DA, Koupilova I, Lithell HO, Berglund L, Mohsen R, Vagero D, et al. Failure to realise growth potential in utero and adult obesity in relation to blood pressure in 50 year old Swedish men. BMJ. 1996 Feb 17;312(7028):401-6.
Barker DJ, Osmond C, Simmonds SJ, Wield GA. The relation of small head circumference and thinness at birth to death from cardiovascular disease in adult life. BMJ. 1993 Feb 13;306(6875):422-6.
Barker DJ, Bull AR, Osmond C, Simmonds SJ. Fetal and placental size and risk of hypertension in adult life. BMJ. 1990 Aug 4;301(6746):259-62.
Lever AF, Harrap SB. Essential hypertension: a disorder of growth with origins in childhood? https://www.ncbi.nlm.nih.gov/pubmed/1313473">J Hypertens. 1992 Feb;10(2):101-20.
Fall CH, Pandit AN, Law CM, Yajnik CS, Clark PM, Breier B, et al. Size at birth and plasma insulin-like growth factor-1 concentrations. Arch Dis Child. 1995 Oct;73(4):287-93.
Ferns GA, Motani AS, Anggård EE. The insulin-like growth factors: their putative role in atherogenesis. Artery. 1991;18(4):197-225.
Folkow B. Structure and function of the arteries in hypertension. https://www.ncbi.nlm.nih.gov/pubmed/3661386">Am Heart J. 1987 Oct;114(4 Pt 2):938-48.
Martyn CN, Greenwald SE. Impaired synthesis of elastin in walls of aorta and large conduit arteries during early development as an initiating event in pathogenesis of systemic hypertension. https://www.ncbi.nlm.nih.gov/pubmed/9314885">Lancet. 1997 Sep 27;350(9082):953-5.
Mañalich R, Reyes L, Herrera M, Melendi C, Fundora I. Relationship between weight at birth and the number and size of renal glomeruli in humans. A histomorphometric study. Kidney Int. 2000 Aug;58(2):770-3.
Hoy WE, Hughson MD, Singh GR, Douglas-Denton R, Bertram JF. Reduced nephrone number and glomerulomegaly in Australian aborigines: A group at high risk for renal disease and hypertension. Kidney Int. 2006 Jul;70(1):104-10. doi: 10.1038/sj.ki.5000397.
Phillips DI, Barker DJ. Association between low birthweight and high resting pulse in adult life: is the sympathetic nervous system involved in programming the insulin resistance syndrome? Diabet Med. 1997 Aug;14(8):673-7. doi: 10.1002/(SICI)1096-9136(199708)14:8<673::AID-DIA458>3.0.CO;2-9
Hales CN, Barker DJ, Clark PM, Cox LJ, Fall C, Osmond C, et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ. 1991 Oct 26;303(6809):1019-22.
Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell UB, Leon DA. Relation of size at birth to non-insulin-dependent diabetes and insulin concentrations in men aged 50–60 years. BMJ. 1996 Feb 17;312(7028):406-10.
Curhan GC, Willett WC, Rimm EB, Spiegelman D, Ascherio AL, Stampfer MJ. Birth weight and adult hypertension and diabetes mellitus in US men. Circulation. 1996 Dec 15;94(12):3246-50.
Leger J, Levy-Marchal C, Bloch J, Pinet A, Chevenne D, Porquet D, et al. Reduced final height and indications for insulin resistance in 20 year olds born small for gestational age: regional cohort study. BMJ. 1997 Aug 9;315(7104):341-7.
Yajnik CS, Fall CH, Vaidya U, Pandit AN, Bavdekar A, Bhat DS, et al. Fetal growth and glucose and insulin metabolism in four-year-old Indian children. Diabet Med. 1995 Apr;12(4):330-6.
Temple RC, Carrington CA, Luzio SD, Owens DR, Schneider AE, Sobey WJ, et al. Insulin deficiency in non-insulin- dependent diabetes. Lancet. 1989 Feb 11;1(8633):293-5.
Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Int J Epidemiol. 2013 Oct;42(5):1215-22. doi: 10.1093/ije/dyt133.
Leger J, Levy-Marchal C, Bloch J, Pinet A, Chevenne D, Porquet D, et al. Reduced final height and indications for insulin resistance in 20 year olds born small for gestational age: regional cohort study. BMJ. 1997 Aug 9;315(7104):341-7.
Taylor DJ, Thompson CH, Kemp GJ, Barnes PR, Sanderson AL, Radda GK, et al. A relationship between impaired fetal growth and reduced muscle glycolysis revealed by 31P magnetic resonance spectroscopy. Diabetologia. 1995 Oct;38(10):1205-12.
Rudolph AM. The fetal circulation and its response to stress. https://www.ncbi.nlm.nih.gov/pubmed/6707438">J Dev Physiol. 1984 Feb;6(1):11-9.
Bjorntorp P. Insulin resistance: the consequence of a neuroendocrine disturbance? Int J Obesity. 1995 May;19(1):S6-10.
Dicke JM. Poor obstetrical outcome. In: Patierstein CJ, editor. Clinical Obstetrics. New York: John Wiley and Sons; 1987;421-439. 73.
Barker DJ, Martyn CN, Osmond C, Hales CN, Fall CH. Growth in utero and serum cholesterol concentrations in adult life. BMJ. 1993 Dec 11;307(6918):1524-7.
Barker DJ, Meade TW, Fall CH, Lee A, Osmond C, Phipps K, et al. Relation of fetal and infant growth to plasma fibrinogen and factor VII concentrations in adult life. BMJ. 1992 Jan 18;304(6820):148-52.
Ozanne SE, Fernandez-Twinn D, Hales CN. Fetal growth and adult diseases. Semin Perinatol. 2004 Feb;28(1):81-7.
. Fowden AL, Giussani DA, Forhead AJ. Intrauterine Programmingof Physiological Systems: Causes and Consequences. Physiology (Bethesda). 2006 Feb;21:29-37. doi: 10.1152/physiol.00050.2005.
Kratzsch J, Höckel M, Kiess W. Leptin and pregnancy outcome. Curr Opin Obstet Gynecol. 2000 Dec;12(6):501-5.
Vickers MH, Krechowec SO, Gluckman PD, Breier BH. The Role of Leptin during Early Life. in Imprinting Later Metabolic Responses. In: Gertler A, editor. Leptin and Leptin Antagonists. Auckland: Landes Bioscience; 2009, р. 141-61.
Whorwood CB, Firth KM, Budge H, Symonds ME. Maternal undernutrition during early to mid-gestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11-beta-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin ІІ receptor in neonatal sheep. Endocrinology. 2001 Jul;142(7):2854-64.
Seckl JR. Glucocorticoid programming of the fetus: adult phenotypes and molecular mechanisms. https://www.ncbi.nlm.nih.gov/pubmed/11738795">Mol Cell Endocrinol. 2001 Dec 20;185(1-2):61-71.
Nosenko ND. Rol' hliukokortykoidiv materyns'koho pokhodzhennia u rozvytku syndromu prenatal'noho stresu [The role of glucocorticoids of maternal origin in the development of prenatal stress syndrome]. Endokrynolohiia. 2001;6:214. (in Ukrainian).
Reznikov AG, Pishak VP, Nosenko ND, Tkachuk SS, Myslitskiy VF. Prenatal'nyy stress i neyroendokrinnaya patologiya [Prenatal stress and neuroendocrine pathology]. Chernovtsy: Medakademiya; 2004. 318 p. (in Russian).
Serhiienko LIu. Sotsial'no-emotsiinyistresmateriv na rannikh etapakh vahitnosti yak prychyna endokrynopatii ta porushen' u hormonal'no zalezhnykh systemakh naschadkiv (eksperymental'ne doslidzhennia) [Socio-emotionalstressmasters in the early stages of pregnancy as a cause of endocrinopathy and disorders in hormonal dependent systems of descendants (experimental study)] [avtoreferat]. Kharkiv; 2013. 42 p. (in Ukrainian).
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