ОСНОВНІ МЕХАНІЗМИ ФОРМУВАННЯ ЕНДОТОКСИКОЗУ ПРИ ПОЛІОРГАННОМУ УШКОДЖЕННІ

Автор(и)

  • A. V. Rybarchuk Вищий державний навчальний заклад України «Буковинський державний медичний університет», м. Чернівці, Ukraine
  • V. M. Konovchuk Вищий державний навчальний заклад України «Буковинський державний медичний університет», м. Чернівці, Ukraine

DOI:

https://doi.org/10.24061/1727-4338.XV.2.56.2016.49

Ключові слова:

синдром поліорганного ушкодження, ендотоксикоз, ендогенна інтоксикація

Анотація

Огляд літератури присвячений актуальним питанням поліорганного ушкодження. Зокрема, представлені основні патогенетичні механізми формування ендотоксикозу як однієї із ключових ланок поліорганного ушкодження.

Посилання

Andreichyn SM, Holomsha TO. Suchasni uiavlennia pro metabolichnu endohennu intoksykatsiiu [Contemporary notions about metabolic endogenous intoxication]. Infektsiini khvoroby. 2012;1:84-7. (in Ukrainian).

Antropova NM. Kombinirovannyj diskretnyj plazmaferez i neprjamoe jelekrohimicheskoe okislenie autoplazmi v kompleksnom lechenii bol'nyh s peritonitom [Combined discrete plasmapheresis and indirect electrochemical oxidation of autoplasms in the complex treatment of patients with peritonitis] [avtoreferat]. Novosibirsk; 2007. 23 s. (in Russian).

Vozniuk VV. Otsinka endotoksykozu pry riznykh patolohichnykh stanakh [Assessment of endotoxicosis in various pathological conditions]. Zhurnal praktychnoho likaria. 2006;4:27-33. (in Ukrainian).

Georgijanc MA, Odinec IJu, Korsunov VA. Intoksikacionnye sindromy v intensivnoj terapii i novye vozmozhnosti ih korrekcii [Intoxication syndromes in intensive care and new opportunities for their correction]. Har'kov; 2008. 45 s. (in Russian).

Golub IE, Sorokina LV, Netesin ES. Poliorgannaja nedostatochnost': ucheb. Posob [Multiple organ failure]. Irkutsk: IGMU. 2011. 25 s . (in Russian).

Danilov IA, Ovechkin AM. Poliorgannaja nedostatochnost': sostojanie problemy i sovremennye metody lechenija s ispol'zovaniem nizkopotochnyh membrannyh tehnologij [Multiple organ failure: the state of the problem and modern methods of treatment using low-flow membrane technologies]. Obshhaja reanimatologija. 2011;6:66-71. (in Russian).

Zhidovinov AA, Zurnadzh'janc VA, Zhidovinov GI, Aleshin DA. Znachenie laboratornyh markerov jendotoksikoza i citokinovogo profilja v diagnostike i jeffektivnosti lechenija oslozhnennyh form ostrogo holecistita [The importance of laboratory markers of endotoxicosis and cytokine profile in the diagnosis and efficacy of treatment of complicated forms of acute cholecystitis]. Citokiny i vospalenie. 2006;3:17-21. (in Russian).

Konovchuk VM, Akentiev SO, Polianskyi IIu. Syndrom poliorhannoho ushkodzhennia pislia hipovolemichnoho posthemorahichnoho shoku [Polyorganic damage syndrome after hypovolemic posthemorrhagic shock]. Bukovynskyi medychnyi visnyk. 2007;11(3):42-5. (in Ukrainian).

Malyj VP. Sepsis v praktike klinicista [Sepsis in the practice of a clinician]. Har'kov: Prapor; 2008. 584 s. (in Russian).

Marino PL. Intensivnaja terapija [Intensive therapy]. Per. s angl. Moskva: GJeOTAR-Media; 2010. 768 s. (in Russian).

Shah BN, Lapshin VN, Teplov VM, Smirnov DB, Kyrnyshev AG. Mehanizmy razvitija poliorgannoj nedostatochnosti pri shokogennoj travme: klinicheskij podhod k probleme [Mechanisms of development of multiple organ failure in a shockogenic trauma: a clinical approach to the problem]. Vestnik hirurgii im. Grekova II. 2011;6:93-7. (in Russian).

Mosencev NN, Mal'ceva LA, Mosencev NF. Sovremennaja shema patofiziologii sepsisa, osnovannaja na analize znachimosti ego biomarkerov [The modern scheme of the pathophysiology of sepsis, based on the analysis of the significance of its biomarkers]. Vestnik intensivnoj terapii. 2010;4:9-16. (in Russian).

Heorhyiants MA, Korsunov VA, Shylova EV. Nediabetychni ketoatsydozy u dytiachomu vitsi. Klinika, diahnostyka ta infuziina terapiia [Non-diabetic ketoacidosis in childhood. Clinic, diagnostics and infusion therapy]: metod. rekomendatsii. Kharkiv; 2009. 27 s. (in Ukrainian).

Rozanov VE, Bolotnikov AI, Hajkin IV, Mazilina AN, Dzhirikova NB, Skachkov AS, i dr. Nekotory mehanizmy razvitija poliorgannoj nedostatochnosti u postradavshih s sochetannoj travmoj zhivota, oslozhnennoj sepsisom [Some mechanisms of the development of multiple organ failure in patients with a combined abdominal trauma complicated by sepsis]. Jefferentnaja terapija. 2009;15(1-2):167-68. (in Russian).

Novak VL, Oborin OM. Syndrom endohennoi intoksykatsii, sepsys y poliorhanna nedostatnist: patofiziolohichni ta klinichni aspekty problemy [Endogenous intoxication syndrome, sepsis and polyorganic insufficiency: pathophysiologic and clinical aspects of the problem]. Zhurnal akademii medychnykh nauk Ukrainy. 2009;15(2):263-75. (in Ukrainian).

Girsh AO, Malkov OA, Lukach VN. O soprjazhennosti pokazatelej jendotoksikoza, immunoreaktivnosti, central'noj gemodinamiki i transporta kisloroda u bol'nyh saharnym diabetom s razlitym peritonitom [On the conjugation of endotoxicosis, immunoreactivity, central hemodynamics and oxygen transport in diabetic patients with diffuse peritonitis]. Intensivnaja terapija. 2005;3:77-82. (in Russian).

Borisov DB, Nedashkovskij JeV. Ocenka tjazhesti i intensivnaja terapija rasprostranennogo peritonita [Assessment of severity and intensive therapy of advanced peritonitis]. Vestnik intensivnoj terapii. 2005;1:5-9. (in Russian).

Nepomnjashhih VA, Lomivorotov VV, Derjagin MN, Knjaz'kova LG, Lomivorotov VN, Novikov MA. Rol' jendogennoj intoksikacii v razvitii poliorgannoj disfunkcii u kardiohirurgicheskih bol'nyh v rannem posleoperacionnom periode [The role of endogenous intoxication in the development of multi-organ dysfunction in cardiosurgical patients in the early postoperative period]. Anesteziol. i reanimatologija. 2011;6:16-20. (in Russian).

Winter V, Czeslick E, Sablotzki A. Sepsis i poliorgannaja nedostatochnost' - patofiziologija i aktual'nye koncepcii lechenija [Sepsis and multiple organ failure - pathophysiology and topical treatment concepts]. Anesteziologija i reanimatologija. 2007;5:66-71. (in Russian).

Savel'ev VS, Gel'fand BR, redaktory. Sepsis v nachale HXI veka. Klassifikacija, kliniko diagnosticheskaja koncepcija i lechenie. Patologo anatomicheskaja diagnostika [Sepsis in the beginning of the ХII century. Classification, clinical diagnostic concept and treatment. Pathological anatomical diagnosis]: prakticheskoe rukovodstvo. Moskva: Litterra; 2006. 176 s. (in Russian).

Serebrjakova EN, Volosnikov DK, Glazyrina GA. Sindrom poliorgannoj nedostatochnosti: sovremennoe sostojanie problemy [Syndrome of multiple organ failure: the current state of the problem]. Vestnik anesteziologii i reanimatologii. 2013;10(5):60-6. (in Russian).

Butt I, Shrestha BM. Two-hit hypothesis and multiple organ dysfunction syndrome. https://www.ncbi.nlm.nih.gov/pubmed/18709037">JNMA J Nepal Med Assoc. 2008 Apr-Jun;47(170):82-5.

Dellinger RP, Levy MM, Rhodes A. Campaign: International Guidelinesfor Management of Severe Sepsis and Septic Shock. Surviving Sepsis: 2012. Intensive Care Medicine. 2013;39:165-228.

Gustot T. Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response. Curr Opin Crit Care. 2011 Apr;17(2):153-9. DOI:10.1097/MCC.0b013e328344b446.

Zhou J, Qian C, Zhao M, Yu X, Kang Y, Ma X, et al. Epidemiology and Outcome of Severe Sepsis and Septic Shock in Intensive Care Unitsin Mainland China. PLoS One. 2014 Sep 16;9(9):e107181. DOI:10.1371/journal.pone.0107181.

Murray MJ, Coursin DB. Multiple organ dysfunction syndrome. Yale J Biol Med. 1993 Sep-Oct; 66(5): 501-10.

Tsukamoto T, Chanthaphavong RS, Pape HC. Current theories on the pathophysiology of multiple organ failure after trauma. Injury. 2010 Jan;41(1):21-6. DOI:10.1016/j.injury.2009.07.010.

Wenzel RP, Edmond MB. Antibiotics for abdominal sepsis. N Engl J Med. 2015 May 21;372(21):2062-3. DOI:10.1056/NEJMe1503936.

Winter V, Czeslick E, Sablotzki A. Sepsis i poliorgannaja nedostatochnost' - patofiziologija i aktual'nye koncepcii lechenija [Sepsis and multiple organ failure - pathophysiology and topical treatment concepts]. Anesteziologija i reanimatologija. 2007;5:66-71.

Yamada Y. Recent understanding of sepsis: mechanisms of organ dysfunction and advances in treatment - preface and comments. Japanese j of anesthesiology. 2008;57(3):276-77.

Barie PS, Hydo LJ, Pieracci FM, Shou J, Eachempati SR. Multiple organ dysfunction syndrome in critical surgical illness. Surg Infect (Larchmt). 2009 Oct;10(5):369-77. DOI:10.1089/sur.2009.9935.

Dünser MW, Bataar O, Tsenddorj G, Lundeg G, Torgersen C, Romand JA, et al. Differences in critical care practice between an industrialized and a developing country. Wien Klin Wochenschr. 2008;120(19-20):600-7.

Fry DE. Sepsis, systemic inflammatory response, and multiple organ dysfunction: the mystery continues. https://www.ncbi.nlm.nih.gov/pubmed/22273282">Am Surg. 2012 Jan;78(1):1-8.

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2018-04-11

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