ОСНОВНІ ПАТОГЕНЕТИЧНІ ЛАНКИ КОМОРБІДНОГО ПЕРЕБІГУ ХРОНІЧНОГО ОБСТРУКТИВНОГО ЗАХВОРЮВАННЯ ЛЕГЕНЬ ТА ХРОНІЧНОГО ПАНКРЕАТИТУ (ОГЛЯД ЛІТЕРАТУРИ)
DOI:
https://doi.org/10.24061/1727-4338.XVI.2.60.2017.22Ключові слова:
хронічне обструктивне захворювання легень, хронічний панкреатит, муковісцидоз, білок трансмембранного регулятора провідності муковісцидозу, курінняАнотація
Мета: основна мета наукового дослідження полягала у проведені поглибленого аналізу даних літературних джерел щодо впливу стану гена МВ (муковісцидозу) на коморбідний перебіг хронічного обструктивного захворювання легень та хронічного панкреатиту.
Висновки: в результаті проведеного аналізу даних літературних джерел встановлено збільшення частоти гетерозиготного носійства мутацій гена муковісцидозу серед осіб із хронічним панкреатитом та патологією бронхолегеневої системи, а саме хворі на бронхіальну астму, бронхоектатичну хворобу у порівнянні із загальною популяцією. Також виявлений негативний вплив тютюнового диму на функцію білка муковісцидозного трансмембранного регулятора, що проявляється згущенням секрету екзокринних залоз.Посилання
Beljalov F.I. Problema komorbidnosti pri zabolevanijah vnutrennih organov [The problem of comorbidity in diseases of internal organs]. Vestnik sovremennoj klinicheskoj mediciny. 2010. Vol. 3 (2). P. 44-47 (in Russian).
Gubergric N.B., Jaroshenko L.A. Dinamika vneshnesekretornoj funkcii podzheludochnoj zhelezy u bol'nyh hronicheskim pankreatitom v sochetanii s hronicheskim bronhitom pod vlijaniem terapii preparatami magnija [Dynamics of the exocrine function of the pancreas in patients with chronic pancreatitis in combination with chronic bronchitis under the influence of therapy with magnesium preparations]. Zhurnal Gastroenterologija. 2013. Vol. 3 (49). S. 1-3 (in Russian).
Dolinchuk L.V., Basanets A.V., Andrushchenko T.A. Henetychni aspekty rozvytku khronichnoho obstruktyvnoho zakhvoriuvannia lehen [Genetic aspects in the development of chronic obstructive pulmonary disease]. Ukrainskyi zhurnal z problem medytsyny pratsi. 2013. Vol. 1 (34). S. 44-56. (in Ukrainian).
Zalinska O.M., Tolubaiev V.V. Doslidzhennia sotsialno-ekonomichnykh aspektiv zbytkovosti vnaslidok khronichnoho obstruktyvnoho zakhvoriuvannia lehen ta bronkhialnoi astmy [The study socio-economic aspects loss due to chronic obstructive pulmonary disease and asthma]. Ukrainskyi pulmonolohichnyi zhurnal. 2011. Vol. 1. S. 33-36. (in Ukrainian).
Kazakov Iu. M., Treumova S.I., Petrov Ie.Ie. Tiutiunopalinnia – etiopatohenetychnyi faktor ryzyku khronichnoho obstruktyvnoho zakhvoriuvannia lehen: ohliad literatury, vlasni doslidzhennia [Smoking - etiopathogenetical risk factor for chronic obstructive pulmonary disease: a review of literature and own research]. Mystetstvo likuvannia. 2014. Vol. 5 (111-112). S. 40-43. (in Ukrainian).
Mostovyi Iu. M., Rasputina L.V., Dovhan A.O., Ovcharuk M.V. Problema komorbidnykh staniv u natsionalnii uhodi z diahnostyky ta likuvannia khronichnoho obstruktyvnoho zakhvoriuvannia lehen iz pozytsii vlasnoho dosvidu. Obhovorennia nakazu №555” [The problem of comorbid conditions in the national agreement for the diagnosis and treatment of chronic obstructive pulmonary disease from a position of personal experience. Discussion of the order №555]. Bukovynskyi medychnyi visnyk. 2014. Vol. 3 (71). S. 221-226. (in Ukrainian).
Mukovistsydoz v Ukraini: problema, shcho potrebuie nehainykh dii: materialy naukovoho sympoziumu z Mizhnarodnoiu uchastiu “Problemni pytannia medychnoi dopomohy ditiam ta pidlitkam” [Problematic issues of care for children and adolescents]. Sovremennaja pediatrija. 2014. Vol. 3 (59). S. 1-2. (in Ukrainian).
Rekomendacii Rossijskoj gastroenterologicheskoj associacii po diagnostike i lecheniju hronicheskogo pankreatita [Recommendations of the Russian gastroenterological association for the diagnosis and treatment of chronic pancreatitis]. RZhGGK. 2013. Vol. 1. S. 66-87. (in Russian).
Rekomendacii po prekrashheniju potreblenija tabaka i lecheniju tabachnoj zavisimosti [Recommendations for cessation of tobacco consumption and treatment of tobacco dependence]. [Internet]. 2013. Available from: http://ensp.org/wp-content/uploads/2016/12/ENSP-GUIDE_RU_COMPLETE-1.pdf. (in Russian).
Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy ta medychnoi reabilitatsii. Khronichne obstruktyvne zakhvoriuvannia lehen [Unified clinical protocols of primary, secondary (specialized), third (highly specialized) care and rehabilitation. Chronic obstructive pulmonary disease]. Nakaz MOZ Ukrainy vid 27.06.2013 № 555. (in Ukrainian).
Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi) medychnoi dopomohy ta medychnoi reabilitatsii. Khronichnyi pankreatyt [Unified clinical protocols of primary, secondary (specialized) care and rehabilitation. Chronic pancreatitis]. Nakaz MOZ Ukrainy vid 10.09.2014 №63. (in Ukrainian).
Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy. Mukovistsydoz [Unified clinical protocols of primary, secondary (specialized), third (highly specialized) medical care. Cystic fibrosis]. Nakaz MOZ Ukrainy vid 15.07.2016 №723. (in Ukrainian).
Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD / M.T. Dransfield, A.M. Wilhelm, B. Flanaqan [et al.] Chest. 2013. №144(2). P. 498-506. doi: 10.1378/chest.13-0274.
Agarwal A., Khan A., Aggarwal A.N. Link between CFTR mutations and ABPA: a systematic review and meta-analysis. Mycoses, diagnosis, therapy and prophylaxis of fungal diseases. 2012. №55(4). P. 357-365. doi: 10.1111/j.1439-0507.2011.02130.x.
A high frequency of the cystic fibrosis 2184insA mutation inWestern Ukraine: genotype-phenotype correlations, relevance and genetic testing / Makukh H., Krenkova P., Tyrkus M. [et al.]. Journal of Cystic Fibrosis. 2010. №9(5). P. 371-375. doi: 10.1016/j.jcf2010.06.001.
Analysis of CFTR gene variants in idiopathic bronchiectasis in Serbian children / Milosevic K. et al. Pediatric Allergy, Immunology and Pulmonology. 2013. №26(2). P. 93-98. doi: 10.1089/ped.2013.02.38.
A new model of cystic fibrosis pathology: lack of transport of glutathione and its thiocyanate conjugates / M. Childers, G. Eckel, A. Himmel, J. Caldwell. Medical Hypotheses. 2007. №68(1). P. 101-12. doi: 10.1016/j.mehy.2006.06.020.
A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lund disease / Sloane P.A. et al. PLoS ONE. 2012. №7(6). doi: 10.1371/journal.pone.0039809.
Association between cystic fibrosis transmembrane conductance regulator gene mutations and susceptibility for childhood asthma in Korea / K.W. Kim, J.H. Lee, M.G. Lee [et al.]. Yonsei Med J. 2010. №51(6). P. 912-917. doi: 10.3349/ymj.2010.51.6.912.
A 10-year large-scale cystic fibrosis carrier screening in the Italian population / Picci L. et al. Journal of Cystic Fibrosis. 2009. - №9(1). P. 29-35. doi: 10.1016/jcf.2009.10.003.
Bodas M., Min T., Vij N. Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physid Lung Cell Mol Physid. 2011. №300(6). P. 811-820. doi:10.1152/ajplung.00408.2010.
Boucher R.C. Evidence for airway surface dehydration as the initiating event in CF airway disease. J Intern Med. 2007. №261(1). P. 5-16. doi:10.1111/j.1365-2796.2006.01744.x.
Cantin A.M., Hanrahan J.W., Bilodeau G. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med. 2006. №173(10). P. 1139-44. doi: 10.1164/rccm.200508-1330oc.
CFTR mutations in men with congenital bilateral absence of the vas deferens (CBAVD): a systemic review and meta-analysis / Yu J., Chen Z., Ni Y., Li Z.. Human Reproduction. 2012. №27(1). P. 25-35. doi: 10.1093/humrep/der 377.
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration / Clunes L.A. et al. FASEB J. 2012. №26(2). P. 533-545. doi: 10.1096/fj.11-192377.
Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis / Schneider A. [et al.]. Gastroenterology. 2011. №140. – P. 162-171. doi: 10.1053/j.gastro.2010.10.045.
Connections between genetics and clinical data: role of MCP-1, CFTR, and SPINK-1 inthe setting of acute, acute recurrent, and chronic pancreatitis / Cavestro G.M. et al. Am J Gastroenterol. 2010. №105(1). P. 199-206. doi: 10.1038/ajg.2009.611.
Chaaban M.R., Kejner A., Rowe S.M., Woodworth B.A. Cystic fibrosis chronic rhinosinusitis: a comprehensive review. American Journal of Rhinology and Allergy. 2013. №27(5). P. 387-95. doi: 10.2500/ajra.2013.27.3919.
Cystic fibrosis foundation: cystic fibrosis patient registry. https://www.cff.org/2014_CFF_Annual_Data_Report_to_the_Center_Directors.
Cystic fibrosis-related diabetes: from CFTR dysfunction to oxidative stress / Ntimbane T. et al. Clin Biochem Rev. 2009. №30(4). P. 153-177. PMCID:PMC 2791770.
Developmental genetics of the COPD lung / K. Probert, S. Miller, A.K. Kheirallah, I.P. Hall. COPD Research and Practice. 2015. doi: 10.1186/s4749-015-0014-x.
Evaluating adults with idiopathic pancreatitis for genetic predisposition / Ballard D.D. et.al. Pancreas J. 2015. №44(1). P. 116-121. doi: 10.1097/MPA.0000000000000225.
Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion / M. Dahn, B.G. Nordestgaard, P. Lange, A. Tybjaerg-Hansen // J Allergy Clin Immunol. 2001. №107(5). P. 818-823. doi: 10.1067/mai.2001.114117.
Hakkak A.M., Keramatipour M., Kianifar R. Analysis of CFTR gene mutations in children with cystic fibrosis, first report from north-east of Iran. Iranian Journal of Basic Medical Sciences. 2013. №16(8). P. 917-921. PMCID:PMC 3786104.
Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis / Raju S.V. et al. Respiratory Research. 2014. №15(1). doi: 10.1186/1465-9921-15-18.
Laboratory standards and guidelines for population-based cystic fibrosis carrier screening / Grody W.W. et at. Genet Med. 2001. №3(2). P. 149-154. doi: 10.1097/00125817-200103000-00010.
Maurya N., Awasthi S., Dixit P. Association of CFTR gene mutation with bronchial asthma. Indian J Med Res. 2012. №135(4). P. 469-478. PMCID:PMC 3385229.
Molecular analysis of cystic fibrosis patients in Hungary – an update to the mutational spectrum / Ivady G. et at. J Med Biochem. 2014. №34(1). P. 46-51. doi: 10.2478/jomb-2014-0055.
Nemeth B.C., Sahin-Toth M. Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2014. №306(6). P. 466-473. doi: 10.1152/ajpgi.00419.2013.
Ooi C.Y., Durie P.R. Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in pancreatitis. Journal of Cystic Fibrosis. 2012. №11(5). P. 355-362. doi: 10.1016/j.jcf.2012.05.001.
Pancreas divisum is not a cause of pancreatitis by itself but acts as a partner of genetic mutations / Bertin C. et. al. Am J Gastroenterol. 2011. №107. P. 311-317. doi:10.1038/ajg.2011.424.
Prasad R., Sharma H., Kaur G. Molecular basis of cystic fibrosis disease: an Indian perspective. Indian J Clin Biochem. 2010. №25(4). P. 335-41. doi: 10.1007/s12291-010-0091-1.
Presence of SPINK-1 variant alters the course of chronic pancreatitis / Sandhu B.et al. J Gastroenterol Hepatol. 2011. №26(6). P. 965-969. doi: 10.1111/j.1440-1746.2011.06713.x.
Ratjen F.A. Cystic fibrosis: pathogenesis and future treatment strategies. Respir Care. 2009. №54(5). P. 595-605. PMID:19393104.
Role of oxygen availability in CFTR expression and function / J.S. et al. Am J Respir Cell Mol Biol. 2008. №39(5). P. 149-154. doi: 10.1097/00125817-200103000-00010.
Stockley R.A. Bronchiectasis with chronic obstructive pulmonary disease: association or a further phenotype. Am J Respir Crit Care Med. 2013. №187(8). – P. 786-788. doi: 10.1164/rccm.201302-0203ED.
Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis / O. Cy, et al. Gastroenterology. 2011. №140(1). P. 153-161. doi: 10.1053/j.gastro2010.09.046.
Watson M.S., Cuttine G.R., Desnick R.J. Cystic fibrosis population carrier screening: 2004 revision of American college of medical genetics mutation panel. Genet Med. 2004. №6(6). P. 387-391. doi: 10.109701.GIM.0000139506.11694.7c.
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