ОСНОВНІ ПАТОГЕНЕТИЧНІ ЛАНКИ КОМОРБІДНОГО ПЕРЕБІГУ ХРОНІЧНОГО ОБСТРУКТИВНОГО ЗАХВОРЮВАННЯ ЛЕГЕНЬ ТА ХРОНІЧНОГО ПАНКРЕАТИТУ (ОГЛЯД ЛІТЕРАТУРИ)

O. S. Khukhlina, O. O. Ursul, O. S. Voyevidka, L. V. Kaniovska, V. S. Gaydichuk, A. V. Andrusiak

Анотація


Мета: основна мета наукового дослідження полягала у проведені поглибленого аналізу даних літературних джерел щодо впливу стану гена МВ (муковісцидозу) на коморбідний перебіг хронічного обструктивного захворювання легень та хронічного панкреатиту.

Висновки: в результаті проведеного аналізу даних літературних джерел встановлено збільшення частоти гетерозиготного носійства мутацій гена муковісцидозу серед осіб із хронічним панкреатитом та патологією бронхолегеневої системи, а саме хворі на бронхіальну астму, бронхоектатичну хворобу у порівнянні із загальною популяцією. Також виявлений негативний вплив тютюнового диму на функцію білка муковісцидозного трансмембранного регулятора, що проявляється згущенням секрету екзокринних залоз.

Ключові слова


хронічне обструктивне захворювання легень; хронічний панкреатит; муковісцидоз; білок трансмембранного регулятора провідності муковісцидозу; куріння

Повний текст:

PDF (English)

Посилання


Beljalov F.I. Problema komorbidnosti pri zabolevanijah vnutrennih organov [The problem of comorbidity in diseases of internal organs]. Vestnik sovremennoj klinicheskoj mediciny. 2010. Vol. 3 (2). P. 44-47 (in Russian).

Gubergric N.B., Jaroshenko L.A. Dinamika vneshnesekretornoj funkcii podzheludochnoj zhelezy u bol'nyh hronicheskim pankreatitom v sochetanii s hronicheskim bronhitom pod vlijaniem terapii preparatami magnija [Dynamics of the exocrine function of the pancreas in patients with chronic pancreatitis in combination with chronic bronchitis under the influence of therapy with magnesium preparations]. Zhurnal Gastroenterologija. 2013. Vol. 3 (49). S. 1-3 (in Russian).

Dolinchuk L.V., Basanets A.V., Andrushchenko T.A. Henetychni aspekty rozvytku khronichnoho obstruktyvnoho zakhvoriuvannia lehen [Genetic aspects in the development of chronic obstructive pulmonary disease]. Ukrainskyi zhurnal z problem medytsyny pratsi. 2013. Vol. 1 (34). S. 44-56. (in Ukrainian).

Zalinska O.M., Tolubaiev V.V. Doslidzhennia sotsialno-ekonomichnykh aspektiv zbytkovosti vnaslidok khronichnoho obstruktyvnoho zakhvoriuvannia lehen ta bronkhialnoi astmy [The study socio-economic aspects loss due to chronic obstructive pulmonary disease and asthma]. Ukrainskyi pulmonolohichnyi zhurnal. 2011. Vol. 1. S. 33-36. (in Ukrainian).

Kazakov Iu. M., Treumova S.I., Petrov Ie.Ie. Tiutiunopalinnia – etiopatohenetychnyi faktor ryzyku khronichnoho obstruktyvnoho zakhvoriuvannia lehen: ohliad literatury, vlasni doslidzhennia [Smoking - etiopathogenetical risk factor for chronic obstructive pulmonary disease: a review of literature and own research]. Mystetstvo likuvannia. 2014. Vol. 5 (111-112). S. 40-43. (in Ukrainian).

Mostovyi Iu. M., Rasputina L.V., Dovhan A.O., Ovcharuk M.V. Problema komorbidnykh staniv u natsionalnii uhodi z diahnostyky ta likuvannia khronichnoho obstruktyvnoho zakhvoriuvannia lehen iz pozytsii vlasnoho dosvidu. Obhovorennia nakazu №555” [The problem of comorbid conditions in the national agreement for the diagnosis and treatment of chronic obstructive pulmonary disease from a position of personal experience. Discussion of the order №555]. Bukovynskyi medychnyi visnyk. 2014. Vol. 3 (71). S. 221-226. (in Ukrainian).

Mukovistsydoz v Ukraini: problema, shcho potrebuie nehainykh dii: materialy naukovoho sympoziumu z Mizhnarodnoiu uchastiu “Problemni pytannia medychnoi dopomohy ditiam ta pidlitkam” [Problematic issues of care for children and adolescents]. Sovremennaja pediatrija. 2014. Vol. 3 (59). S. 1-2. (in Ukrainian).

Rekomendacii Rossijskoj gastroenterologicheskoj associacii po diagnostike i lecheniju hronicheskogo pankreatita [Recommendations of the Russian gastroenterological association for the diagnosis and treatment of chronic pancreatitis]. RZhGGK. 2013. Vol. 1. S. 66-87. (in Russian).

Rekomendacii po prekrashheniju potreblenija tabaka i lecheniju tabachnoj zavisimosti [Recommendations for cessation of tobacco consumption and treatment of tobacco dependence]. [Internet]. 2013. Available from: http://ensp.org/wp-content/uploads/2016/12/ENSP-GUIDE_RU_COMPLETE-1.pdf. (in Russian).

Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy ta medychnoi reabilitatsii. Khronichne obstruktyvne zakhvoriuvannia lehen [Unified clinical protocols of primary, secondary (specialized), third (highly specialized) care and rehabilitation. Chronic obstructive pulmonary disease]. Nakaz MOZ Ukrainy vid 27.06.2013 № 555. (in Ukrainian).

Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi) medychnoi dopomohy ta medychnoi reabilitatsii. Khronichnyi pankreatyt [Unified clinical protocols of primary, secondary (specialized) care and rehabilitation. Chronic pancreatitis]. Nakaz MOZ Ukrainy vid 10.09.2014 №63. (in Ukrainian).

Unifikovanyi klinichnyi protokol pervynnoi, vtorynnoi (spetsializovanoi), tretynnoi (vysokospetsializovanoi) medychnoi dopomohy. Mukovistsydoz [Unified clinical protocols of primary, secondary (specialized), third (highly specialized) medical care. Cystic fibrosis]. Nakaz MOZ Ukrainy vid 15.07.2016 №723. (in Ukrainian).

Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD / M.T. Dransfield, A.M. Wilhelm, B. Flanaqan [et al.] Chest. 2013. №144(2). P. 498-506. doi: 10.1378/chest.13-0274.

Agarwal A., Khan A., Aggarwal A.N. Link between CFTR mutations and ABPA: a systematic review and meta-analysis. Mycoses, diagnosis, therapy and prophylaxis of fungal diseases. 2012. №55(4). P. 357-365. doi: 10.1111/j.1439-0507.2011.02130.x.

A high frequency of the cystic fibrosis 2184insA mutation inWestern Ukraine: genotype-phenotype correlations, relevance and genetic testing / Makukh H., Krenkova P., Tyrkus M. [et al.]. Journal of Cystic Fibrosis. 2010. №9(5). P. 371-375. doi: 10.1016/j.jcf2010.06.001.

Analysis of CFTR gene variants in idiopathic bronchiectasis in Serbian children / Milosevic K. et al. Pediatric Allergy, Immunology and Pulmonology. 2013. №26(2). P. 93-98. doi: 10.1089/ped.2013.02.38.

A new model of cystic fibrosis pathology: lack of transport of glutathione and its thiocyanate conjugates / M. Childers, G. Eckel, A. Himmel, J. Caldwell. Medical Hypotheses. 2007. №68(1). P. 101-12. doi: 10.1016/j.mehy.2006.06.020.

A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lund disease / Sloane P.A. et al. PLoS ONE. 2012. №7(6). doi: 10.1371/journal.pone.0039809.

Association between cystic fibrosis transmembrane conductance regulator gene mutations and susceptibility for childhood asthma in Korea / K.W. Kim, J.H. Lee, M.G. Lee [et al.]. Yonsei Med J. 2010. №51(6). P. 912-917. doi: 10.3349/ymj.2010.51.6.912.

A 10-year large-scale cystic fibrosis carrier screening in the Italian population / Picci L. et al. Journal of Cystic Fibrosis. 2009. - №9(1). P. 29-35. doi: 10.1016/jcf.2009.10.003.

Bodas M., Min T., Vij N. Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physid Lung Cell Mol Physid. 2011. №300(6). P. 811-820. doi:10.1152/ajplung.00408.2010.

Boucher R.C. Evidence for airway surface dehydration as the initiating event in CF airway disease. J Intern Med. 2007. №261(1). P. 5-16. doi:10.1111/j.1365-2796.2006.01744.x.

Cantin A.M., Hanrahan J.W., Bilodeau G. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am J Respir Crit Care Med. 2006. №173(10). P. 1139-44. doi: 10.1164/rccm.200508-1330oc.

CFTR mutations in men with congenital bilateral absence of the vas deferens (CBAVD): a systemic review and meta-analysis / Yu J., Chen Z., Ni Y., Li Z.. Human Reproduction. 2012. №27(1). P. 25-35. doi: 10.1093/humrep/der 377.

Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration / Clunes L.A. et al. FASEB J. 2012. №26(2). P. 533-545. doi: 10.1096/fj.11-192377.

Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis / Schneider A. [et al.]. Gastroenterology. 2011. №140. – P. 162-171. doi: 10.1053/j.gastro.2010.10.045.

Connections between genetics and clinical data: role of MCP-1, CFTR, and SPINK-1 inthe setting of acute, acute recurrent, and chronic pancreatitis / Cavestro G.M. et al. Am J Gastroenterol. 2010. №105(1). P. 199-206. doi: 10.1038/ajg.2009.611.

Chaaban M.R., Kejner A., Rowe S.M., Woodworth B.A. Cystic fibrosis chronic rhinosinusitis: a comprehensive review. American Journal of Rhinology and Allergy. 2013. №27(5). P. 387-95. doi: 10.2500/ajra.2013.27.3919.

Cystic fibrosis foundation: cystic fibrosis patient registry. https://www.cff.org/2014_CFF_Annual_Data_Report_to_the_Center_Directors.

Cystic fibrosis-related diabetes: from CFTR dysfunction to oxidative stress / Ntimbane T. et al. Clin Biochem Rev. 2009. №30(4). P. 153-177. PMCID:PMC 2791770.

Developmental genetics of the COPD lung / K. Probert, S. Miller, A.K. Kheirallah, I.P. Hall. COPD Research and Practice. 2015. doi: 10.1186/s4749-015-0014-x.

Evaluating adults with idiopathic pancreatitis for genetic predisposition / Ballard D.D. et.al. Pancreas J. 2015. №44(1). P. 116-121. doi: 10.1097/MPA.0000000000000225.

Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion / M. Dahn, B.G. Nordestgaard, P. Lange, A. Tybjaerg-Hansen // J Allergy Clin Immunol. 2001. №107(5). P. 818-823. doi: 10.1067/mai.2001.114117.

Hakkak A.M., Keramatipour M., Kianifar R. Analysis of CFTR gene mutations in children with cystic fibrosis, first report from north-east of Iran. Iranian Journal of Basic Medical Sciences. 2013. №16(8). P. 917-921. PMCID:PMC 3786104.

Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis / Raju S.V. et al. Respiratory Research. 2014. №15(1). doi: 10.1186/1465-9921-15-18.

Laboratory standards and guidelines for population-based cystic fibrosis carrier screening / Grody W.W. et at. Genet Med. 2001. №3(2). P. 149-154. doi: 10.1097/00125817-200103000-00010.

Maurya N., Awasthi S., Dixit P. Association of CFTR gene mutation with bronchial asthma. Indian J Med Res. 2012. №135(4). P. 469-478. PMCID:PMC 3385229.

Molecular analysis of cystic fibrosis patients in Hungary – an update to the mutational spectrum / Ivady G. et at. J Med Biochem. 2014. №34(1). P. 46-51. doi: 10.2478/jomb-2014-0055.

Nemeth B.C., Sahin-Toth M. Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2014. №306(6). P. 466-473. doi: 10.1152/ajpgi.00419.2013.

Ooi C.Y., Durie P.R. Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in pancreatitis. Journal of Cystic Fibrosis. 2012. №11(5). P. 355-362. doi: 10.1016/j.jcf.2012.05.001.

Pancreas divisum is not a cause of pancreatitis by itself but acts as a partner of genetic mutations / Bertin C. et. al. Am J Gastroenterol. 2011. №107. P. 311-317. doi:10.1038/ajg.2011.424.

Prasad R., Sharma H., Kaur G. Molecular basis of cystic fibrosis disease: an Indian perspective. Indian J Clin Biochem. 2010. №25(4). P. 335-41. doi: 10.1007/s12291-010-0091-1.

Presence of SPINK-1 variant alters the course of chronic pancreatitis / Sandhu B.et al. J Gastroenterol Hepatol. 2011. №26(6). P. 965-969. doi: 10.1111/j.1440-1746.2011.06713.x.

Ratjen F.A. Cystic fibrosis: pathogenesis and future treatment strategies. Respir Care. 2009. №54(5). P. 595-605. PMID:19393104.

Role of oxygen availability in CFTR expression and function / J.S. et al. Am J Respir Cell Mol Biol. 2008. №39(5). P. 149-154. doi: 10.1097/00125817-200103000-00010.

Stockley R.A. Bronchiectasis with chronic obstructive pulmonary disease: association or a further phenotype. Am J Respir Crit Care Med. 2013. №187(8). – P. 786-788. doi: 10.1164/rccm.201302-0203ED.

Type of CFTR mutation determines risk of pancreatitis in patients with cystic fibrosis / O. Cy, et al. Gastroenterology. 2011. №140(1). P. 153-161. doi: 10.1053/j.gastro2010.09.046.

Watson M.S., Cuttine G.R., Desnick R.J. Cystic fibrosis population carrier screening: 2004 revision of American college of medical genetics mutation panel. Genet Med. 2004. №6(6). P. 387-391. doi: 10.109701.GIM.0000139506.11694.7c.


Пристатейна бібліографія ГОСТ






DOI: https://doi.org/10.24061/1727-4338.XVI.2.60.2017.22

Посилання

  • Поки немає зовнішніх посилань.


© Clinical & Experimental Pathology, 2004-2018
When you copy an active link to the material is required
ISSN 2521-1153 (Online)
ISSN 1727-4338 (Print)
tel./fax +38(0372)553754